A continuously-updating model of you — fused from every signal modern
medicine can capture, and capable of asking the questions a clinician
would, if they could sit with you for a decade.
2026 frontierintelligent twins — reasoning, learning, decision-making models that interact with other digital representationsfoundation models on multi-omics — pretrained on millions of profiles, fine-tuned per individualgenerative in-silico avatars — simulating treatment response before it touches a bodycontinuous bidirectional sync — physical-to-virtual, virtual-to-physical13% reduction in cardiac arrhythmia recurrence with twin-guided ablation97% accuracy in early neurodegenerative trajectory predictionsub-millisecond liver response simulation2026 frontierintelligent twins — reasoning, learning, decision-making models that interact with other digital representationsfoundation models on multi-omics — pretrained on millions of profiles, fine-tuned per individualgenerative in-silico avatars — simulating treatment response before it touches a bodycontinuous bidirectional sync — physical-to-virtual, virtual-to-physical13% reduction in cardiac arrhythmia recurrence with twin-guided ablation97% accuracy in early neurodegenerative trajectory predictionsub-millisecond liver response simulation
Six engines, one twin.
Most "AI health" products bolt one model onto a dashboard. Averra is a
stack — six engines, in continuous bidirectional dialogue with the
physical you. Each is built at the frontier; together, they form
something the field has been chasing for two decades.
01 · Cognitioni.
A personal foundation model.
A pretrained transformer over millions of multi-omics and clinical
profiles, fine-tuned on you. A resting heart rate of 58 means
something specific to your biology — not the population average.
This is what the field calls an intelligent twin: a model
that reasons, learns and decides, not a database that reports.
Frontier alignmentFMs · multi-omics integration
02 · Sensingii.
Continuous multimodal fusion.
Wearables, glucose, sleep, labs, imaging, microbiome, mood,
environment — normalised into a single time-aware record. The twin
works because the constellation does, not because any one biomarker
tells the truth.
Streams14 modalities · 1 record
03 · Predictioniii.
Forward trajectories, with honest confidence.
1, 5 and 25-year horizons expressed as ranges, not single points
pretending to be certainty. A confidence cone widens with
uncertainty and narrows as new evidence arrives — the way a careful
clinician actually thinks.
Horizons1y · 5y · 25y
04 · Reasoningiv.
Counterfactual simulation, in your numbers.
Generative in-silico avatars — patient-specific simulations of how a
change in sleep, training load, or pharmacology would propagate
through your physiology. The twin answers what changes for me?,
rehearsed virtually before anything is rehearsed in vivo.
EngineQSP · mechanistic + learned
05 · Sovereigntyv.
Federated, never extracted.
Your raw data never leaves your sovereign vault. The twin learns
locally; only encrypted gradients return to the population model.
This is what makes the platform deployable in regulated systems —
NHS, EMA, HIPAA — without the data-governance bottlenecks that
stall every other foundation-model rollout in healthcare.
ComplianceFHIR · GDPR · SOC 2 · HIPAA
06 · Privacyvi.
Zero-knowledge by construction.
Homomorphic encryption on inference, secure multi-party computation
on cohort queries, attestable enclaves on training. The twin can
answer questions about you without anyone — including us — being
able to read you.
CryptographyFHE · SMPC · TEE
Where the field is, and where we sit.
— 2002
Mirror twin
Static digital replicas. NASA aerospace doctrine, ported to medicine.
Self-adaptive models with continuous wearable + omics sync.
2026 — now
Intelligent twin
Reasoning, learning, decision-making. Foundation-model spine. This is where Averra lives.
For the clinician
A second opinion that never sleeps.
Doctors don't need another dashboard. They need a colleague who has
read every page of a patient's chart, every lab from every quarter,
every wearable trace since onboarding — and who can answer
questions in the cadence of a real consultation.
Averra surfaces the twin to clinicians as a structured second
opinion: ranked hypotheses, the evidence behind each one, and
counterfactual scenarios the doctor can rehearse before
prescribing. The clinician remains in the loop. The twin earns its
confidence by being right, repeatedly, in their own caseload.
"It is the difference between reading a patient's notes and
actually understanding them. The twin doesn't replace the
consultation — it gives me ten years of context in the first
ninety seconds."
— Consultant cardiologist · pilot cohort, 2026
M· Patient 0241Twin v4.2 · synced 12s ago
Biological age
41.6 yrs
▼ 2.3 vs chronological
VO₂ max
52 ml/kg/min
▲ 3.1 / 90d
HRV (RMSSD)
68 ms
▲ steady
ApoB
98 mg/dL
▲ trending up
Twin · hypothesis
Cardiometabolic drift — ApoB trajectory crosses
the 100 mg/dL threshold at roughly 14 months on
current behaviour. Counterfactual: shifting evening meal
composition (− saturated fat, + Zone-2 frequency) moves
crossover beyond 5-year horizon with 0.81 confidence.
Twin · flag
Sleep architecture has shortened slow-wave fraction
for 11 of last 14 nights. Not yet clinical, but cohort priors
associate this pattern with HRV regression at 8-week lag.
Worth raising in next consult.
Every signal — no signal alone.
A single biomarker rarely tells the truth. The twin is precise
because the constellation is — heart rate variability read against
sleep architecture, against training load, against last quarter's
bloodwork, against a decade of family history.
α
Continuous
Streams from wearables, rings, patches and continuous glucose monitors.
HR · HRV
Resp
Temp
Sleep stages
CGM
β
Episodic
Quarterly bloodwork, imaging panels, gut and hormonal markers.
Bloodwork
MRI / DXA
Microbiome
Hormones
γ
Static
Genome, family history, lifelong clinical record, prescriptions.
WGS
Methylome
EHR
Family hx
δ
Contextual
Training, nutrition, mood, environment — the variables most studies discard.